The Combination of Colocasia esculenta L. and Zingiber officinale Potentially Inhibits Inflammation and Pain

The active metabolites of Colocasia esculenta L. and Zingiber officinale have been reported to reduce pain exert anti-inflammatory effects. This study aimed examine the analgesic effects a combination C. Z. extract. Thirty rats mice were each divided into 6 groups (n=5), namely normal group, negative control, positive control (Nadiclofenac), 3 test given extract (dose 1.3 mg/20 gBW, 2.6 5.2 gBW). Winter's method was used for tests by inducing carrageenan in rat paws, Sigmund's intraperitoneal induction acetic acid mice. percentage inhibition leg edema 11.33%, 18.90%, 19.10% three doses combined extracts officinale, 22.72% Na-diclofenac (p<0.05). group 61.17%, 41.19%, 51.79%, 52.35%, respectively exhibited Dose gBW as effective Na-diclofenac.